Thermo Fisher Scientific Periostin Monoclonal Antibody (OTI2D10), Biotin, TrueMAB
인간 Periostin 단백질을 인식하는 Mouse IgG1 단클론 항체로 ELISA 및 Luminex 분석에 적합. Biotin으로 표지된 TrueMAB 형식이며 고순도 친화 크로마토그래피 정제. 연구용으로만 사용 가능, 안정적인 액상 형태로 보관 용이.
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Applications
ELISA
- Tested Dilution: 1:250–1:1,000
Luminex
- Tested Dilution: Assay-Dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2D10 |
| Immunogen | Full length human recombinant protein of human POSTN produced in HEK293T cell |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 10 mg/mL BSA, 50% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Additional Formats
Target Information
Periostin (PN), also known as osteoblast-specific factor 2 (OSF-2), is a disulfide-linked protein originally identified as an osteoblast-specific factor. It is a secreted protein that binds heparin and acts as a ligand for α(V)β(3) and α(V)β(5) integrins. In preosteoblasts, Periostin functions as a cell adhesion molecule, contributing to osteoblast recruitment, spreading, and attachment.
Periostin is mainly expressed in the lower gastrointestinal tract, aorta, stomach, placenta, uterus, and breast tissues, but is up-regulated in epithelial ovarian tumors and overexpressed in breast cancer. Its expression increases in response to bone morphogenetic protein (BMP2) and transforming growth factor β1 (TGF-β1). Structurally, Periostin contains a signal sequence, a cysteine-rich domain, four fasciclin-like repeats, and a C-terminal domain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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