Thermo Fisher Scientific FGFR1 Polyclonal Antibody, Biotin
FGFR1 단백질을 인식하는 Biotin 결합 Rabbit Polyclonal Antibody입니다. Western blot, ELISA, Immunoprecipitation에 적합합니다. 고순도 Affinity chromatography로 정제되었으며, 인체 및 Rat 시료에 반응합니다. 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 640–690 on human basic fibroblast growth factor receptor protein 1 |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 0.5% BSA, 30% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
FGFR1 (also known as FLT2) is a member of the Fibroblast Growth Factor Receptor family, consisting of four membrane-spanning tyrosine kinases (FGFR1–4) that serve as high-affinity receptors for 17 growth factors (FGF1–17). The FGF receptor family plays an important role in biological processes such as mesoderm induction, cell growth, migration, organ formation, and bone growth.
FGFR1 undergoes alternative splicing, producing multiple variants expressed differently during embryonic and adult stages. Mutations or aberrations in FGFR1 are linked to diseases such as Pfeiffer syndrome, idiopathic hypogonadotropic hypogonadism (IHH), Kallmann syndrome type 2 (KAL2), osteoglophonic dysplasia (OGD), and others. Chromosomal abnormalities involving FGFR1 are associated with stem cell myeloproliferative disorder and stem cell leukemia lymphoma syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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