Thermo Fisher Scientific TEK VHH-8His-Cys-tag Recombinant Alpaca Monoclonal Antibody (SAA1254)
Recombinant alpaca VHH monoclonal antibody targeting human TEK/TIE-2 receptor. Compatible with direct ELISA. Purified by metal-chelate chromatography, supplied as liquid in PBS without preservative. Stable at 4°C short term and -20°C long term.
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Thermo Fisher Scientific TEK VHH-8His-Cys-tag Recombinant Alpaca Monoclonal Antibody (SAA1254)
Applications
- ELISA (Assay-dependent)
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Alpaca / VHH |
| Expression System | CHO cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SAA1254 |
| Immunogen | Recombinant Human CD202b/TEK/TIE-2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Metal-chelate chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
Product Specific Information
- Compatible with Direct ELISA
Target Information
The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells. TEK signaling is critical for endothelial cell–smooth muscle cell communication in venous morphogenesis, and defects in TEK are associated with inherited venous malformations.
The ligand angiopoietin-1 binds to this receptor and mediates a signaling pathway involved in embryonic vascular development.
Immunoblotting showed that TIE2 expression was increased by thyroid-stimulating hormone and agents that increased intracellular cAMP.
HSCs expressing the receptor tyrosine kinase TIE2 are quiescent and antiapoptotic and comprise a side population of HSCs that adhere to osteoblasts in the bone marrow niche.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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