Thermo Fisher Scientific HDAC2 Polyclonal Antibody, MaxPab

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000

-

Immunocytochemistry (ICC/IF)

30 µg/mL

-

in situ PLA (PLA)

1:1200

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

HDAC2 (AAI48798.1, 1 a.a. approximately 582 a.a) full-length human protein. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:HDAC2,uniProtId:Q92769-1,ncbiNodeId:9606,antigenRange:1-488,antigenLength:488,antigenImageFileName:H00003066-D01P_HDAC2_Q92769-1_Rabbit.svg,antigenImageFileNamePDP:H00003066-D01P_HDAC2_Q92769-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: MRSPPCGLLR WFGGPLLASW CRCHLRFRAF GTSAGWYRAF PAPPPLLPPA CPSPRDYRPH VSLSPFLSRP SRGGSSSSSS SRRRSPVAAV AGEPMAYSQG GGKKKVCYYY DGDIGNYYYG QGHPMKPHRI RMTHNLLLNY GLYRKMEIYR PHKATAEEMT KYHSDEYIKF LRSIRPDNMS EYSKQMQRFN VGEDCPVFDG LFEFCQLSTG GSVAGAVKLN RQQTDMAVNW AGGLHHAKKS EASGFCYVND IVLAILELLK YHQRVLYIDI DIHHGDGVEE AFYTTDRVMT VSFHKYGEYF PGTGDLRDIG AGKGKYYAVN FPMRDGIDDE SYGQIFKPII SKVMEMYQPS AVVLQCGADS LSGDRLGCFN LTVKGHAKCV EVVKTFNLPL LMLGGGGYTI RNVARCWTYE TAVALDCEIP NELPYNDYFE YFGPDFKLHI SPSNMTNQNT PEYMEKIKQR LFENLRMLPH APGVQMQAIP EDAVHEDSGD EDGEDPDKRI SIRASDKRIA CDEEFSDSED EGEGGRRNVA DHKKGAKKAR IEEDKKETED KKTDVKEEDK SKDNSGEKTD TKGTKSEQLS NP

Target Information

HDAC2 belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events. Alternative splicing results in multiple transcript variants.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.