Thermo Fisher Scientific Phospho-4EBP1 (Ser65) Polyclonal Antibody
Phospho-4EBP1 (Ser65) 인산화 단백질 검출용 폴리클로날 항체로, Western blot 및 Immunoprecipitation에 적합. Human, Mouse, Rat 등 다양한 종에 반응. 고순도 항원 친화 크로마토그래피로 정제된 액상 제품. 연구용으로만 사용.
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Thermo Fisher Scientific Phospho-4EBP1 (Ser65) Polyclonal Antibody
Applications and Tested Dilutions
- Western Blot (WB): 1:1,000
- Immunoprecipitation (IP): 1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic phosphopeptide corresponding to the sequence of mouse 4E-BP1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 80 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100 µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10982384 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
This gene encodes one member of a family of translation repressor proteins. The protein interacts directly with eukaryotic translation initiation factor 4E (eIF4E), a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5′ end of mRNAs. Interaction with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals, including UV irradiation and insulin signaling, leading to its dissociation from eIF4E and activation of mRNA translation.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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