Thermo Fisher Scientific TSPAN8 Monoclonal Antibody (458811)
인간 TSPAN8 단백질을 표적으로 하는 Rat IgG2b 단클론 항체. Western blot, IHC, ICC/IF, Flow cytometry 등 다양한 응용 가능. Lyophilized 형태로 공급되며 PBS + 5% trehalose buffer에 보관. 암 관련 연구용으로 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | - |
| Immunocytochemistry (ICC/IF) | 3–25 µg/mL |
| Flow Cytometry (Flow) | 0.25 µg per million cells |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rat / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 458811 |
| Immunogen | NS0 mouse myeloma cell line transfected with human TSPAN8 Met1–Lys237 (Ile35Val) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.5 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2609273 |
Product Specific Information
Reconstitute at 0.5 mg/mL in sterile PBS.
Target Information
TSPAN8 (tetraspanin 8), also known as TM4SF3 or CO-029, is a 237 amino acid multi-pass membrane protein belonging to the tetraspanin family. It plays a role in signal transduction influencing cell development, activation, growth, and motility. Localized to the cell membrane, TSPAN8 is expressed in colon, gastric, renal, and pancreatic cancers, suggesting involvement in cancer formation and metastasis.
The gene encoding TSPAN8 maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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