Thermo Fisher Scientific TSPAN8 Monoclonal Antibody (458811)

Applications

Tested Dilution

Publications

Western Blot (WB)

2 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

-

View 1 publication 1 publication

Immunocytochemistry (ICC/IF)

3-25 µg/mL

-

Flow Cytometry (Flow)

0.25 µg per million cells

-

Product Specifications

Species Reactivity

Human

Published species

Human

Host/Isotype

Rat / IgG2b

Class

Monoclonal

Type

Antibody

Clone

458811

Immunogen

NS0 mouse myeloma cell line transfected with human TSPAN8 Met1-Lys237 (Ile35Val) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:TSPAN8,uniProtId:P19075-1,ncbiNodeId:9606,antigenRange:1-237,antigenLength:237,antigenImageFileName:MA5-24179_TSPAN8_P19075-1_Rat.svg,antigenImageFileNamePDP:MA5-24179_TSPAN8_P19075-1_Rat_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

0.5 mg/mL

Purification

Protein A/G

Storage buffer

PBS with 5% trehalose

Contains

No Preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2609273

Product Specific Information

Reconstitute at 0.5 mg/mL in sterile PBS.

Target Information

TSPAN8 (tetraspanin 8), also known as TM4SF3 or CO-029, is a 237 amino acid multi-pass membrane protein that belongs to the tetraspanin family of transmembrane proteins and is thought to play a role in signal transduction events that influence cell development, activation, growth and motility. Localized to the cell membrane, TSPAN8 is expressed in colon, gastric, renal and pancreatic cancers, strongly suggesting a role in cancer formation and metastasis. The gene encoding TSPAN8 maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.