Thermo Fisher Scientific Thyroglobulin Humanized Recombinant Human Monoclonal Antibody (SAA0534)
인간화된 재조합 단일클론 항체로, Thyroglobulin 검출에 특이적입니다. IHC, ICC/IF, ELISA, RIA, SPR 등 다양한 분석에 사용 가능합니다. CHO 세포에서 발현되며, Protein A/G로 정제된 고순도 항체입니다. 연구용으로만 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunocytochemistry (ICC/IF) | Assay-dependent |
| ELISA | Assay-dependent |
| Radioimmune Assays (RIA) | Assay-dependent |
| Surface Plasmon Resonance (SPR) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Human / VHH-hFc |
| Expression System | CHO cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SAA0534 |
| Immunogen | Recombinant Human TG/Thyroglobulin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
Product Specific Information
Compatible with Direct ELISA.
Target Information
Human thyroglobulin (hTg) is a high molecular weight glycoprotein (605 kDa) found in thyroid follicular cells. It plays a central role in the uptake, incorporation, and regulated biosynthesis of thyroid hormones T4 and T3. Thyroid disorders are largely autoimmune in origin, and anti-thyroglobulin autoantibodies were the first to be discovered. Anti-hTG is found in all thyroid autoimmune diseases (Hashimoto thyroiditis, Graves disease), with the highest levels observed in Hashimoto thyroiditis. Anti-hTG is also characteristic of thyroid cancer, and its determination can be used for the follow-up of cancer patients.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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