Thermo Fisher Scientific Notch1 Polyclonal Antibody

Applications

Immunohistochemistry (IHC)

• Tested Dilution: 1:200–1:600

Product Specifications

Target Information

The notch gene family encodes transmembrane proteins with multiple cysteine-rich EGF-like repeats in the extracellular region. Four mammalian notch genes (Notch1, Notch2, Notch3, Notch4/Int-3) are involved in differentiation of the nervous system and other tissues. EGF-like proteins Delta and Serrate act as ligands for Notch1. Mature Notch proteins are heterodimeric receptors formed by cleavage of precursor proteins into an extracellular subunit (NEC) and a transmembrane subunit (Ntm).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.