Thermo Fisher Scientific MTRR Polyclonal Antibody
MTRR 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. WB, IHC, ICC/IF, IP 등 다양한 응용에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, -20°C 보관. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| Immunoprecipitation (IP) | 1–5 µL/mg of lysate |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E. coli-derived Human MTRR fragment |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Antigen affinity chromatography, Protein A |
| Storage Buffer | PBS, pH 7 |
| Contains | 0.03% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2902696 |
Target Information
Methionine is an essential amino acid required for protein synthesis and one-carbon metabolism. Its synthesis is catalyzed by the enzyme methionine synthase, which can become inactive due to oxidation of its cob(I)alamin cofactor. The protein encoded by the MTRR gene regenerates functional methionine synthase via reductive methylation. It belongs to the ferredoxin-NADP(+) reductase (FNR) family of electron transferases. Mutations in this gene are associated with cbl-E complementation group disorders affecting folate/cobalamin metabolism. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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