Thermo Fisher Scientific GPR17 Monoclonal Antibody (OTI18H2), TrueMAB
GPR17 단백질을 인식하는 마우스 단클론 항체로, IHC(P)에서 1:150 희석으로 사용 가능합니다. 인간 시료에 반응하며, 합성 펩타이드를 면역원으로 제작되었습니다. 액상 형태로 -20°C에서 보관하며, 연구용으로만 사용됩니다.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI18H2 |
| Immunogen | Synthetic peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
The G-protein-coupled receptor (GPCR) superfamily consists of approximately 600–1,000 members and represents the largest known class of molecular targets with proven therapeutic value.
GPR17 is an orphan G protein-coupled receptor involved in the orchestration of oligodendrocyte differentiation and myelination in the central nervous system. It is expressed in brain, kidney, heart, and umbilical vein endothelial cells.
GPR17 exhibits dual specificity for uracil nucleotides and cysteinyl leukotrienes and signals through G(i) protein by inhibiting adenylyl cyclase. It may mediate brain damage by nucleotides and cysteinyl leukotrienes following ischemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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