Thermo Fisher Scientific DYNC1I1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human DYNC1I1. Recombinant protein control fragment (Product #RP-103419). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:DYNC1I1,uniProtId:O14576-1,ncbiNodeId:9606,antigenRange:135-187,antigenLength:645,antigenImageFileName:PA5-63981_DYNC1I1_O14576-1_Rabbit.svg,antigenImageFileNamePDP:PA5-63981_DYNC1I1_O14576-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2640844

Product Specific Information

Immunogen sequence: LQSDSELGRR LHKLGVSKVT QVDFLPREVV SYSKETQTPL ATHQSEEDEE DEE

Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 98%.

Target Information

Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCNT1. May play a role in mediating the interaction of cytoplasmic dynein with membranous organelles and kinetochores.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.