Thermo Fisher Scientific APOBR Monoclonal Antibody (OTI2E6), TrueMAB
인간 APOBR 단백질을 인식하는 Mouse monoclonal antibody. Western blot에 최적화되어 있으며, 1:2,000 희석 비율로 사용 가능. 고순도 Affinity chromatography 정제. 안정적인 PBS/BSA/glycerol buffer에 보관되며 -20°C에서 장기 저장 가능.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2E6 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 780–1088 of human APOBR produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
Macrophage receptor that binds to the apolipoprotein B48 (APOB) of dietary triglyceride (TG)-rich lipoproteins (TRL) or to a similar domain of APOB in hypertriglyceridemic very low density lipoprotein (HTG-VLDL).
Binds and internalizes TRL outside the macrophage context and may provide essential lipids to reticuloendothelial cells.
Could also be involved in foam cell formation with elevated TRL and remnant lipoprotein (RLP).
Mediates rapid high-affinity uptake of chylomicrons (CM), HTG-VLDL, and trypsinized VLDL devoid of APOE in vitro in macrophages.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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