Thermo Fisher Scientific BAMBI Polyclonal Antibody
BAMBI 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western Blot, IHC, ICC/IF, ELISA 등 다양한 응용에 사용 가능. Human, Mouse, Pig, Rat 반응성. 고순도 Protein A 정제 및 안정적 액상 형태로 제공.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Pig, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human BAMBI, amino acids 101–200 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
BAMBI (BMP and activin membrane-bound inhibitor homolog, NMA) is a membrane-spanning glycoprotein that acts as a negative regulator of TGF-beta signaling during development. BAMBI transcription is regulated by beta-catenin, BMP, smad3, and smad4. Its expression increases in colorectal and hepatocellular carcinomas compared to non-cancerous tissues and is highly expressed during odontogenesis. BAMBI is coexpressed with Bmp-4 during early Xenopus embryogenesis and can be detected in poorly metastatic human melanoma cell lines.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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