Thermo Fisher Scientific RORC Monoclonal Antibody (OTI1G3), TrueMAB
Human RORC 단백질(aa 1-266)을 면역원으로 한 Mouse monoclonal antibody. Western blot에 1:2,000 희석 비율로 사용 가능. Affinity chromatography로 정제된 액상 항체로, 1 mg/mL 농도. PBS, BSA, glycerol buffer에 보관하며 -20°C에서 보존.
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Applications
- Western Blot (WB): 1:2,000 dilution tested
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1G3 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–266 of human RORC produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
ROR gamma is a 560 amino acid DNA-binding transcription factor belonging to the ROR/RZR orphan nuclear receptor subfamily. It functions as a ligand-activated transcription factor and is essential for lymphoid organogenesis (lymph nodes and Peyer’s patches). ROR gamma regulates apoptosis during thymopoiesis, inhibits Fas ligand and IL2 expression, and directs differentiation of proinflammatory IL-17+ T helper cells. It shares 50–51% sequence identity with RORA and RORB and is 88% identical to mouse ROR gamma. Highly expressed in skeletal muscle and at lower levels in other tissues.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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