Thermo Fisher Scientific LRIG1 Polyclonal Antibody
LRIG1 단백질을 인식하는 Thermo Fisher Scientific의 토끼 다클론 항체로, Western blot 및 ELISA에 적합합니다. 인간과 생쥐 시료에 반응하며, 종양 억제 관련 연구에 유용합니다. 액상 형태로 제공되며, -20°C에서 보관합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 816–1093 of human LRIG1 (NP_0563562) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.47 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2804408 |
Product Specific Information
Immunogen sequence:
YQTRKKSEEY SVTNTDETVV PPDVPSYLSS QGTLSDRQET VVRTEGGPQA NGHIESNGVC PRDASHFPEP DTHSVACRQP KLCAGSAYHK EPWKAMEKAE GTPGPHKMEH GGRVVCSDCN TEVDCYSRGQ AFHPQPVSRD SAQPSAPNGP EPGGSDQEHS PHHQCSRTAA GSCPECQGSL YPSNHDRMLT AVKKKPMASL DGKGDSSWTL ARLYHPDSTE LQPASSLTSG SPERAEAQYL LVSNGHLPKA CDASPESTPL TGQLPGKQRV PLLLAPKS
Positive Samples: Raji, Mouse skin, Mouse brain
Cellular Location: Membrane, Single-pass type I membrane protein
Target Information
LRIG1 protein (UniProt ID: Q96JA1) is encoded by a gene located on chromosome band 3p14.3, a region frequently deleted in various human cancers. LRIG1 functions as a tumor suppressor gene and encodes an integral cell-surface membrane protein expressed in specific human tissues. The 143-kDa LRIG1 protein may be cleaved into 111-kDa and 32-kDa fragments and is implicated in the inhibition of glial tumor growth. Down-regulation of LRIG1 expression may contribute to tumor development and progression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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