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Thermo Fisher Scientific GCH1 Monoclonal Antibody (OTI2D12), TrueMAB
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Thermo Fisher Scientific GCH1 Monoclonal Antibody (OTI2D12), TrueMAB

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GCH1 단백질을 인식하는 Mouse IgG2a 단클론 항체로, Western blot 및 IHC(P) 적용 가능. 인간 시료 반응성. 고순도 친화 크로마토그래피 정제. 연구용으로만 사용.

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pk
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마지막 업데이트 2025. 08. 05. 오전 10:56
Thermo Fisher Scientific TA810248 GCH1 Monoclonal Antibody (OTI2D12), TrueMAB 100 ul pk판매 단위 pk ·
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600,200원VAT 포함 660,220원

Thermo Fisher Scientific · Thermo Fisher Scientific GCH1 Monoclonal Antibody (OTI2D12), TrueMAB

Applications

  • Western Blot (WB): 1:2,000
  • Immunohistochemistry (Paraffin) (IHC (P)): 1:500

Product Specifications

항목 내용
Species Reactivity Human
Host / Isotype Mouse / IgG2a
Class Monoclonal
Type Antibody
Clone OTI2D12
Immunogen Full length human recombinant protein of human GCH1 produced in E.coli
Conjugate Unconjugated
Form Liquid
Concentration 1 mg/mL
Purification Affinity chromatography
Storage Buffer PBS with 1% BSA, 50% glycerol
Contains 0.02% sodium azide
Storage Conditions -20°C, Avoid Freeze/Thaw Cycles
Shipping Conditions Ambient (domestic); Wet ice (international)

Target Information

This gene encodes a member of the GTP cyclohydrolase family. The encoded protein is the first and rate-limiting enzyme in tetrahydrobiopterin (BH4) biosynthesis, catalyzing the conversion of GTP into 7,8-dihydroneopterin triphosphate.
BH4 is an essential cofactor required by aromatic amino acid hydroxylases as well as nitric oxide synthases.
Mutations in this gene are associated with malignant hyperphenylalaninemia and dopa-responsive dystonia.
Several alternatively spliced transcript variants encoding different isoforms have been described; however, not all variants give rise to a functional enzyme.


For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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