Thermo Fisher Scientific ZMYM2 Polyclonal Antibody
ZMYM2 단백질을 인식하는 Rabbit Polyclonal 항체로, WB 및 ICC/IF에 사용 가능. Human, Mouse, Rat에 반응하며, 항원 친화 크로마토그래피로 정제됨. PBS 버퍼에 0.02% sodium azide 포함, 2–8°C 보관 권장.
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- pk
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.125–0.25 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 17 amino acid peptide near the amino terminus of human ZMYM2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage, store at -20°C. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11152210 |
Product Specific Information
- Suggested positive control: rat lung tissue lysate
- PA5-21090 can be used with blocking peptide PEP-1204
- The immunogen is located within amino acids 120–170 of ZMYM2
Target Information
ZNF198 is a ubiquitously expressed nuclear protein whose physiological role is largely unknown. It consists of 5 N-terminal zinc finger motifs responsible for protein-protein interactions, a central proline-rich domain, and a C-terminal nuclear localization signal (NLS) and acidic domain. Reciprocal chromosomal translocation involving ZNF198 and FGFR1 results in the formation of the ZNF198/FGFR1 fusion kinase protein. This fusion protein is a ligand-dependent, constitutively active cytoplasmic tyrosine kinase and regulates several STAT transcription factors including STAT1, STAT3, and STAT5. This fusion protein is oncogenic and associated with atypical myeloproliferative disease, peripheral blood eosinophilia, and T-cell leukemia/lymphoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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