Thermo Fisher Scientific ELOVL1 Polyclonal Antibody
ELOVL1 단백질을 인식하는 Rabbit Polyclonal Antibody로, Human 및 Mouse 시료에 반응합니다. Western blot과 Immunocytochemistry에 적합하며, 고순도 친화 크로마토그래피로 정제되었습니다. PBS/glycerol buffer에 보관되며 -20°C에서 안정적으로 유지됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human ELOVL1 (Accession Q9BW60), corresponding to amino acid residues V108–I158 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2853681 |
Product Specific Information
Antibody detects endogenous levels of total ELOVL1.
Target Information
Elongation of very long chain fatty acid-like (ELOVL) proteins 1–6 are members of the ELO family of proteins, which play an important role in tissue-specific biosynthesis of very long chain fatty acids and sphingolipids.
ELOVL proteins act as catalysts in fatty acid elongation reduction and localize to the endoplasmic reticulum (ER).
ELOVL1 (also known as Ssc1) is the human homolog of the yeast ELO3 protein. It is expressed in multiple tissues, with high levels in stomach, skin, intestine, kidney, and lung.
ELOVL1 participates in the elongation of very long chain saturated and monounsaturated fatty acids (up to 26 carbons) and may be required for epithelial barrier and skin development.
It is also important for myelin formation in the central nervous system. Impaired ELOVL1 activity may be associated with sphingolipid metabolism disorders.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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