Thermo Fisher Scientific RAB11A/RAB11B Polyclonal Antibody
RAB11A/RAB11B 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체입니다. Western blot, IHC, ICC/IF, ELISA에 사용 가능하며, 높은 특이성과 재현성을 제공합니다. 인간, 생쥐, 랫드 반응성. 연구용으로만 사용됩니다.
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Thermo Fisher Scientific RAB11A/RAB11B Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 1–100 of human RAB11A/RAB11B (NP_0046541) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.507 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914276 |
Product Specific Information
Positive test controls include: A-549, Mouse brain, Mouse heart, Rat liver, Rat heart.
Immunogen sequence:
MGTRDDEYDY LFKVVLIGDS GVGKSNLLSR FTRNEFNLES KSTIGVEFAT RSIQVDGKTI KAQIWDTAGQ ERYRAITSAY YRGAVGALLV YDIAKHLTYE
Target Information
Rab11A is a member of the YPT-1 subfamily of Ras-related GTP-binding proteins. Rab11A mRNA is expressed in various tissues including brain, testis, spleen, heart, and gastrointestinal mucosa. In the gastric fundus, Rab11A localizes to parietal cell tubulovesicles membranes and apical vesicular populations in epithelial cells. It plays essential roles in:
- Resecretion of alpha-synuclein via endosome recycling
- Exocytosis of bladder umbrella cell vesicles
- Biogenesis of Birbeck granules
- Endosomal activation of PI3K/AKT signaling via G beta gamma trafficking
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일: PA5-120704_RAB11ARAB11B_Q15907-1_Rabbit_PDP.jpeg, PA5-120704_RAB11ARAB11B_P62491-1_Rabbit_PDP.jpeg)
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