Thermo Fisher Scientific TRPM5 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1026-1165 of human TRPM5 (NP_0553701) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:TRPM5,uniProtId:Q9NZQ8-1,ncbiNodeId:9606,antigenRange:1026-1165,antigenLength:1165,antigenImageFileName:PA5-88498_TRPM5_Q9NZQ8-1_Rabbit.svg,antigenImageFileNamePDP:PA5-88498_TRPM5_Q9NZQ8-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.84 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2804955

Product Specific Information

Immunogen sequence: RVFKKEAEHK REHLERDLPD PLDQKVVTWE TVQKENFLSK MEKRRRDSEG EVLRKTAHRV DFIAKYLGGL REQEKRIKCL ESQINYCSVL VSSVADVLAQ GGGPRSSQHC GEGSQLVAAD HRGGLDGWEQ PGAGQPPSDT; Positive Samples: U-87MG, Mouse liver, Mouse brain; Cellular Location: Cell membrane, Multi-pass membrane protein

Target Information

This gene encodes a member of the transient receptor potential protein family, which is a diverse group of proteins with structural features typical of ion channels. This protein plays an important role in taste transduction, and has characteristics of a calcium-activated, non-selective cation channel that carries Na+, K+, and Cs+ ions equally well, but not Caions. It is activated by lower concentrations of intracellular Ca, and inhibited by higher concentrations. It is also a highly temperature-sensitive, heat activated channel showing a steep increase of inward currents at temperatures between 15 and 35 degrees Celsius. This gene is located within the Beckwith-Wiedemann syndrome critical region-1 on chromosome 11p15. 5, and has been shown to be imprinted, with exclusive expression from the paternal allele.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.