Thermo Fisher Scientific IRAK-M Recombinant Rabbit Monoclonal Antibody (23GB875)
IRAK-M 단백질을 인식하는 토끼 유래 재조합 단클론 항체. Western blot, ICC/IF, Flow Cytometry에 적합. HEK293F 발현 시스템 사용, Affinity chromatography로 정제. PBS/glycerol buffer에 보관, -20°C 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 |
| Immunocytochemistry (ICC/IF) | 1:1,000 |
| Flow Cytometry (Flow) | 1:2,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293F |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 23GB875 |
| Immunogen | A synthetic peptide of human IRAK3 (550–596AA) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
Target Information
IRAK3 (Interleukin-1 receptor-associated kinase 3) is a serine/threonine kinase and a member of the interleukin-1 receptor-associated kinase family, essential for Toll/IL-R immune signal transduction. It is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. IRAK3 plays a critical role in innate immunity and is implicated in immunocompromised states during sepsis. Mutations in IRAK3 are associated with asthma susceptibility.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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