Thermo Fisher Scientific TACI Polyclonal Antibody
Human TACI 단백질을 인식하는 Rabbit Polyclonal Antibody로 IHC(P) 및 ELISA에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, 동결건조 형태로 제공. BAFF 및 April 관련 B세포 면역 반응 연구에 적합.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 2–5 µg/mL
ELISA
- Tested Dilution: 1–5 µg/mL (capture)
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E. coli-derived human TACI recombinant protein (Position: M1–S165) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 500 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 4 mg trehalose |
| Contains | 0.05 mg sodium azide |
| Storage Conditions | −20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2747261 |
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Target Information
Members of the TNF superfamily regulate immune responses and induce apoptosis. Two novel members, BAFF (also known as BLyS, TALL-1, THANK, zTNF4) and APRIL (also known as TALL-2), have been identified.
BAFF acts as a B cell activator, inducing proliferation and immunoglobulin secretion, while APRIL regulates both immunological and non-immunological cell growth.
Three receptors—BCMA, TACI, and BAFF-R—bind BAFF and APRIL. TACI, similar to BCMA, binds both ligands and plays a role in regulating humoral immune responses, activating NF-kappa-B and c-Jun N-terminal kinase, and is implicated in B cell-associated autoimmune diseases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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