Thermo Fisher Scientific TPM2 Polyclonal Antibody
TPM2 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot, IHC, ICC/IF, ELISA에 사용 가능. Human, Mouse, Rat에 반응하며, Protein A로 정제된 액상 형태. 연구용으로 근육 수축 관련 단백질 연구에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:200 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human TPM2 (amino acids 11–130) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
TPM2 (Tropomyosin 2) is beta-tropomyosin, an isoform mainly expressed in slow, type 1 muscle fibers. It binds to actin filaments in muscle and non-muscle cells and plays a central role, in association with the troponin complex, in the calcium-dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. Mutations in this gene can cause nemaline myopathy 4, arthrogryposis distal 1A/2B, and cap myopathy 2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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