Thermo Fisher Scientific SARS-CoV-2 Spike S1 Chimeric Recombinant Human Monoclonal Antibody (hIgM2001)

Thermo Fisher Scientific SARS-CoV-2 Spike S1 Chimeric Recombinant Human Monoclonal Antibody (hIgM2001)

Applications

• ELISA

Tested Dilution: 0.1–10 µg/mL

Product Specifications

Product Specific Information

SARS-CoV-2 (Severe acute respiratory syndrome coronavirus 2), also known as 2019-nCoV, is a positive-sense single-stranded RNA virus that caused COVID-19.
The virus contains a glycosylated spike (S) protein composed of S1 and S2 subunits.
The S1 subunit includes a receptor-binding domain (RBD) that binds to the ACE2 receptor on target cells.
SARS-CoV-2 Spike S1 Antibody (hIgM2001), Human Chimeric, is produced from cell culture in vitro under conditions free from animal-derived components.

Target Information

SARS-CoV-2 (2019-nCoV) causes illnesses ranging from mild cold-like symptoms to severe respiratory distress and death.
The Spike protein consists of S1 and S2 domains and serves as the main surface antigen of the coronavirus.
The glycosylated Spike and nucleocapsid proteins can be detected in infected cell culture supernatants using antisera from SARS patients.
S1 contains an RBD that specifically binds to angiotensin-converting enzyme 2 (ACE2) on target cells.
Coronavirus diversity is reflected in variations of Spike proteins, which differ in receptor interactions and responses to environmental triggers of virus-cell membrane fusion.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.