Thermo Fisher Scientific CDC6 Monoclonal Antibody (OTI1B3), TrueMAB
인간 CDC6 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western blot에 최적화되어 있습니다. 고순도 친화 크로마토그래피 정제, 액상 형태, -20°C 보관. DNA 복제 개시 단계 연구용으로 적합.
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1B3 |
| Immunogen | Full length human recombinant CDC6 protein produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in the cell nucleus during the G1 phase but translocates to the cytoplasm at the start of the S phase. The subcellular translocation of this protein during the cell cycle is regulated through phosphorylation by Cdks. Transcription of this protein is reported to be regulated in response to mitogenic signals through transcriptional control involving E2F proteins.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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