Thermo Fisher Scientific TRIB1 Polyclonal Antibody
TRIB1 단백질을 인식하는 Rabbit Polyclonal Antibody로, 인간 시료에 반응합니다. ICC/IF에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. PBS 기반 완충액에 보관되며, 단기 4°C, 장기 -20°C 저장이 권장됩니다.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human TRIB1. Recombinant protein control fragment (Product # RP-107301) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2664485 |
Product Specific Information
Immunogen sequence:
VRSAMSGASQP RGPALLFPAT RGVPAKRLLD ADDAAAVAAK CPRLSECSSP PDYLSPP
- Highest antigen sequence identity to the following orthologs:
- Mouse: 88%
- Rat: 90%
Target Information
TRIB1 (also known as G protein coupled receptor induced, SKIP1, GIG2, C8FWATP) participates in protein binding, protein kinase inhibitor activity, and protein serine/threonine kinase activities.
Overexpression of TRIB1 in HeLa cells represses IL8 promoter activity by inhibiting AP1. It also inhibits Ras-driven and MEKK1-mediated AP1 activation, while enhancing ERK activation.
Interactions have been observed between MEK1 and TRIB1/3, and between MKK4 and TRIB1, suggesting TRIB-MAPKK interactions stabilize TRIB1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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