Thermo Fisher Scientific HERV Polyclonal Antibody
Human HERV(ERVWE1) 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot과 Immunohistochemistry에 사용 가능. 2 mg/mL 농도의 액상 형태이며, PBS buffer에 sodium azide 포함. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 400–429 amino acids from the central region of human HERV (ERVWE1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Size-exclusion, Dialysis, Ammonium sulfate precipitation |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2101528 |
Target Information
HERVs are a class of multiple sclerosis–associated retroviruses.
This antibody reacts with a replication-competent Human Endogenous Retrovirus (HERVW) isolated from placenta.
The synthetic peptide sequence used as immunogen is derived from the virus envelope polyprotein sequence.
Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection.
Endogenous envelope proteins may have kept, lost, or modified their original function during evolution.
The HERVW endogenous envelope protein retains fusogenic properties and participates in trophoblast fusion during placenta morphogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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