Thermo Fisher Scientific GRASP1 Monoclonal Antibody (OTI2C11)
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Applications
Tested Dilution
Publications
Western Blot (WB)
1:1,000
Immunocytochemistry (ICC/IF)
1:100
Flow Cytometry (Flow)
1:100
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse / IgG1
Class
Monoclonal
Type
Antibody
Clone
OTI2C11
Immunogen
Full length human recombinant protein of GRIPAP1 produced in HEK293T cell if (typeof window.$mangular === undefined
|| !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{
targetFamily:
GRASP1,
uniProtId:
Q4V328-1,
ncbiNodeId:
9606,
antigenRange:
1-841,
antigenLength:
841,
antigenImageFileName:
MA5-25032_GRASP1_Q4V328-1_House_mouse.svg,
antigenImageFileNamePDP:
MA5-25032_GRASP1_Q4V328-1_House_mouse_PDP.jpeg,
sortOrder:
1}\]
; $mangular.isB2BCMGT = false
; $mangular.isEpitopesModalImageMultiSizeEnabled = true
;
View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}
Conjugate
Unconjugated Unconjugated Unconjugated
Form
Liquid
Concentration
0.5 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 1% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2724397
Target Information
PDZ domain-containing proteins, such as PSD-95 and GRIP are thought to play key roles in glutamate receptor plasticity. GRIP-associated proteins (GRASPs) that bind to distinct PDZ domains within GRIP also play key roles in regulation of glutamate receptor function. GRASP-1 is a neuronal rasGEF associated with GRIP and AMPA receptors in vivo (Scannevin and Huganir, 2000). Recent work suggests that GRASP-1 may regulate neuronal ras signaling and contribute to the regulation of AMPA receptor distribution by NMDA receptor activity (Ye et al., 2000).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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