Thermo Fisher Scientific Pannexin 1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:400

-

Immunohistochemistry (IHC)

1:300

-

Product Specifications

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Peptide (C)KEPTEPKFKGLRLE, corresponding to amino acid residues 18- 31 of human Pannexin 1 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Pannexin 1,uniProtId:Q96RD7-1,ncbiNodeId:9606,antigenRange:18-31,antigenLength:426,antigenImageFileName:PA5-77358_Pannexin_1_Q96RD7-1_Rabbit.svg,antigenImageFileNamePDP:PA5-77358_Pannexin_1_Q96RD7-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

0.8 mg/mL

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2736320

Product Specific Information

Product is shipped at room temperature as a lyophilized powder and should be stored at -20 °C upon receipt. Reconstitution: add 50 µL of deionized water.

Target Information

The pannexin gene family encodes a second class of putative gap junction proteins and are highly conserved in invertebrates and mammals. Pannexins (Panx) are four-pass transmembrane proteins that oligomerize to form large pore ion and metabolite-permeable channels. Pannexin-1 (PANX1) and Pannexin-3 are closely related, while Pannexin-2 is a more distant relation. PANX1 is a transmembrane protein that forms a mechanosensitive ATP-permeable channel between adjacent cells and in the endoplasmic reticulum. PANX1 may play a role as a Ca2+ -leak channel to regulate ER Ca2+ homeostasis and regulates neural stem and progenitor cell proliferation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.