Thermo Fisher Scientific rRNA Monoclonal Antibody (Y10b), HRP

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

Assay-Dependent

-

Product Specifications

Species Reactivity

All

Host/Isotype

Mouse / IgG3, kappa

Class

Monoclonal

Type

Antibody

Clone

Y10b

Immunogen

The whole 5.8S ribosomal RNA.

Conjugate

HRP HRP HRP

View additional formats

• Unconjugated
• Biotin
• DyLight 488
• DyLight 550
• DyLight 650
• Request custom conjugation

Form

Liquid

Concentration

0.77 mg/mL

Purification

Protein A

Storage buffer

PBS

Contains

no preservative

Storage conditions

4° C, store in dark

Shipping conditions

Wet ice

RRID

AB_11154988

Target Information

rRNA (ribosomal RNA) forms a major structural component of ribosomes which provides a mechanism for decoding mRNA information into amino acids/proteins through the process of translation. rRNA plays a key role in accurate positioning of mRNA as well as peptidyl tRNA, and also plays a structural role in peptidyl transferase activity by generating scaffolds where ribosomal proteins are assembled. rRNA is generated inside nucleolus, which is localized in nucleus of the cells and contains genes essential for encoding rRNA. Defective rRNA may implicate in certain pathologies, for example: decreased rRNA expression has been observed in subjects with myelodysplastic syndromes, and abnormal rRNA expression has also been linked to Alzheimer`s disease.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.