Thermo Fisher Scientific Human IL-6 Recombinant Protein, eBioscience

Applications

Tested Dilution

Publications

Control (Ctrl)

Assay-Dependent

-

Miscellaneous PubMed (Misc)

-

View 2 publications 2 publications

Product Specifications

Species

Human

Published species

Not Applicable

Expression System

E. coli

Amino acid sequence

Human IL-6 recombinant protein contains 184 amino acids

Molecular weight

20.9 kDa

Class

Recombinant

Type

Protein

Purity

>97%

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Purification

purified

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20°C

Shipping conditions

Wet ice

Product Specific Information

Description: Interleukin-6 is a potent lymphoid cell growth factor that affects B-lymphocytes, T-lymphocytes, and hybridoma cells. It will also affect cytotoxic T-cells in combination with other factors such as IL-2 and IFN-gamma. Recombinant human IL-6 is a 20.9 kDa protein containing 184 amino acid residues.

Purity: >97%.

Molecular Weight: 20.9 kDa.

Target Information

IL-6 is a gene that encodes a cytokine that plays a role in inflammation and the maturation of B cells. The protein produced by this gene is an endogenous pyrogen that can induce fever in people with autoimmune diseases or infections. The gene is primarily expressed at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. Elevated levels of the encoded protein have been found in virus infections, including COVID-19 (disease caused by SARS-CoV-2). Diseases associated with IL6 include Kaposi Sarcoma and Rheumatoid Arthritis, Systemic Juvenile.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.