Thermo Fisher Scientific ASCC1 Polyclonal Antibody
Human ASCC1 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P)에서 1:25~1:100 희석으로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol 버퍼에 보관. ASCC1 복합체 관련 유전자 연구에 적합.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:25–1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Fusion protein corresponding to residues near the C-terminal of human activating signal cointegrator 1 complex subunit 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2635808 |
Product Specific Information
This antibody detects endogenous levels of total ASCC1 protein.
Target Information
The ASCC1 gene encodes a subunit of the activating signal cointegrator 1 (ASC-1) complex, a transcriptional coactivator involved in gene transactivation by multiple transcription factors including AP-1, NF-kB, and SRF.
The encoded protein contains an N-terminal KH-type RNA-binding motif essential for AP-1 transactivation by the ASC-1 complex.
Mutations in this gene are associated with Barrett esophagus and esophageal adenocarcinoma.
Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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