Thermo Fisher Scientific Phospho-DNM1L (Ser616) Polyclonal Antibody
Thermo Fisher Scientific의 Phospho-DNM1L (Ser616) Polyclonal Antibody는 인간 DRP1 단백질의 Ser616 인산화 부위를 인식하는 항체입니다. Western blot 및 ELISA에 적합하며, 세포 내 미토콘드리아 분열 연구에 유용합니다. 고순도 친화성 크로마토그래피로 정제된 액상 항체입니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphorylated peptide around S616 of human DRP1 (NP_036192.2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.31 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914877 |
Product Specific Information
- Positive test controls include: HeLa
- Target localization: Cytoplasm, Cytoplasmic vesicle, Endomembrane system, Golgi apparatus, Membrane, Mitochondrion outer membrane, Peripheral membrane protein, Peroxisome, clathrin-coated pit, cytosol, secretory vesicle, synaptic vesicle membrane
- Immunogen sequence: PASPQ
Target Information
Human dynamin-related protein DRP1 contributes to mitochondrial division in mammalian cells.
It plays a critical role in mitochondrial fission both at steady state and during apoptosis.
DRP1 is essential for proper cellular distribution of mitochondria, and in mutant neurons, mitochondria are largely absent from synapses, providing a genetic tool to assess mitochondrial roles in synaptic function.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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