Thermo Fisher Scientific Cdk6 Monoclonal Antibody (4F7)
Cdk6 단백질을 표적하는 Rabbit 모노클로날 항체(클론 4F7)로, WB, IHC, ICC/IF에 사용 가능. 세포주기 관련 연구에 적합하며, 고농도(1 mg/mL) 액상 형태로 제공. -20°C 보관 및 Wet ice 배송.
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Thermo Fisher Scientific Cdk6 Monoclonal Antibody (4F7)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:200 |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4F7 |
| Immunogen | Recombinant human Cdk6 protein, full length |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
Target Information
CDK6 functions as a cell-cycle initiator protein and is coexpressed and copurified with Cyclin D1. They are critical regulators of cell cycle progression. The prototype member of this family, p34cdc2, and a related protein cdk2, function late in the cycle, while cdk4 and cdk6 are critically involved in G1 to S progression.
CDK6 is essential for cell proliferation within the dentate gyrus of the hippocampus and the cuventricular zone of the lateral ventricles. Mutations in the gene result in microcephaly 12, primary, autosomal recessive (MCPH12).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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