Thermo Fisher Scientific FSBP Polyclonal Antibody
Human FSBP 단백질에 특이적인 Rabbit Polyclonal Antibody로, Western blot 및 IHC(P)에서 검증됨. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:20–1:50 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human FSBP. Recombinant protein control fragment (Product #RP-93950). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2641756 |
Product Specific Information
Immunogen sequence:
SNISEPTKKV MEMIPQISSF CLVRDRNHIQ SANLDEEAQA GTSSLQVMLD HHPVAITVEV KQEEDIKPPP PLVLNSQQSD TLEQREEHEL VHVMERSLSP
Highest antigen sequence identity to the following orthologs:
- Mouse: 83%
- Rat: 81%
Target Information
Protein: Fibrinogen silencer-binding protein (FSBP)
Function: Transcriptional repressor that down-regulates expression of the fibrinogen gamma chain. Represses transcription of GSK3B gene promoter via interaction with APBA1.
Subunit structure: Interacts with APBA1 (via PDZ 1 and 2 domains).
Subcellular location: Nucleus.
Tissue specificity: Expressed in multiple tissues including brain.
Miscellaneous: Located in the second intron of RAB54B gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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