Thermo Fisher Scientific ROR gamma Polyclonal Antibody
ROR gamma 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 Immunocytochemistry에 사용 가능. Human에 반응하며, Mouse와 Bovine에 예측 반응. 항원 친화 크로마토그래피로 정제된 액상 제품으로, 단기 4°C, 장기 -20°C 보관 권장.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein fragment corresponding to a region within amino acids 95–301 of Human ROR gamma |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 1% BSA, 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2546363 |
Product Specific Information
- Recommended positive controls: 293T, HeLa, HepG2, ROR gamma-transfected 293T
- Predicted reactivity: Mouse (80%), Bovine (83%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
ROR gamma is a 560 amino acid DNA-binding transcription factor belonging to the ROR/RZR orphan nuclear receptor subfamily. Reports suggest that ROR gamma is a ligand-activated transcription factor essential for lymphoid organogenesis (lymph nodes and Peyer’s patches) and may play a regulatory role in apoptosis during thymopoiesis. It inhibits Fas ligand and IL2 expression and directs differentiation of proinflammatory IL-17+ T helper cells. ROR gamma shares 50–51% sequence identity with RORA and RORB and is 88% identical to mouse ROR gamma. It is highly expressed in skeletal muscle and at lower levels in other tissues.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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