Thermo Fisher Scientific DDX20 Polyclonal Antibody
Rabbit polyclonal antibody against human DDX20 (Gemin 3) for IHC and IHC-P applications. Antigen affinity purified, supplied as liquid form at 0.25 mg/mL. Predicted cross-reactivity with multiple mammalian species. For research use only.
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Applications
Immunohistochemistry (IHC)
- Tested dilution: 1:100–1:500
Immunohistochemistry (Paraffin) (IHC-P)
- Tested dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residues 600–650 of human DEAD (Asp-Glu-Ala-Asp) Box 20 (Gemin 3) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.25 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, predicted to react with Horse, Pig, Panda, Orangutan, Monkey, Gorilla, Chimpanzee, Thirteen-lined ground squirrel, and Small-eared galago
Target Information
Gemin 3 (DDX20) is a member of the DEAD box protein family, characterized by the conserved Asp-Glu-Ala-Asp (DEAD) motif. These proteins are putative RNA helicases involved in RNA secondary structure modification processes such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly.
Some DEAD box proteins are implicated in embryogenesis, spermatogenesis, and cellular growth and division. Gemin 3 exhibits ATPase activity and functions as a component of the survival of motor neurons (SMN) complex, potentially playing a catalytic role in RNP function.
Dysfunction of Gemin 3 is associated with spinal muscular dystrophy and muscular atrophy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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