Thermo Fisher Scientific ACTG1 Monoclonal Antibody (1G6)
ACTG1 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체로, Human 시료에 반응합니다. ELISA 및 in situ PLA에 사용 가능하며, 액상 형태로 제공됩니다. 친화 크로마토그래피로 정제되었으며, -20°C에서 보관합니다.
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Applications
ELISA (ELISA)
- Tested Dilution: 1 ng/mL
in situ PLA (PLA)
- Tested Dilution: 1:1200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1G6 |
| Immunogen | ACTG1 (AAH53572, 1 a.a. ~ 375 a.a) full-length recombinant protein with GST tag. MW of GST tag: 26 kDa |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein Sequence:
MEEEIAALVI DNGSGMCKAG FAGDDAPRAV FPSIVGRPRH QGVMVGMGQK DSYVGDEAQS KRGILTLKYP IEHGIVTNWD DMEKIWHHTF YNELRVAPEE HPVLLTEAPL NPKANREKMT QIMFETFNTP AMYVAIQAVL SLYASGRTTG IVMDSGDGVT HTVPIYEGYA LPHAILRLDL AGRDLTDYLM KILTERGYSF TTTAEREIVR DIKEKLCYVA LDFEQEMATA ASSSSLEKSY ELPDGQVITI GNERFRCPEA LFQPSFLGME SCGIHETTFN SIMKCDVDIR KDLYANTVLS GGTTMYPGIA DRMQKEITAL APSTMKIKII APPERKYSVW IGGSILASLS TFQQMWISKQ EYDESGPSIV HRKCF
Target Information
Actins are highly conserved proteins involved in cell motility and cytoskeleton maintenance.
Three main actin isoforms exist in vertebrates: alpha, beta, and gamma.
- Alpha actins: Found in muscle tissue, major component of the contractile apparatus.
- Beta and gamma actins: Present in most cell types, function in cytoskeleton structure and internal motility.
- Actin gamma 1 (ACTG1)* is a cytoplasmic actin expressed in all cell types.
Mutations in this gene are linked to DFNA20/26 (autosomal dominant non-syndromic progressive hearing loss) and Baraitser-Winter syndrome.
Alternative splicing produces multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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