Thermo Fisher Scientific STK38 Polyclonal Antibody
Thermo Fisher Scientific의 STK38 Polyclonal Antibody는 인간 및 생쥐 시료에 반응하는 rabbit polyclonal 항체로, WB, ICC/IF, ELISA에 적합합니다. 고순도 친화 크로마토그래피 정제, 액상 형태, -20°C 보관 조건을 갖습니다.
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- PA5110442
- 판매단위
- pk
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 366–465 of human STK38 (NP_0092021) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.29 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2855853 |
Product Specific Information
Immunogen sequence: ILKPTVATSN HPETDYKN
Target Information
STK38 (also known as NDR, Nuclear Dbf2-related protein) is a serine/threonine kinase belonging to the AGC kinase family, regulated by Mob proteins. It is activated by Fas and TNFα receptor stimulation through phosphorylation at the hydrophobic motif. STK38 functions as a pro-apoptotic kinase and is a key component of the RASSF1A/MST1 signaling cascade. It plays a crucial role in mitotic chromosome alignment fidelity, is incorporated into HIV-1 particles, and cleaved by the HIV-1 protease. STK38-driven centrosome duplication requires Cdk2 activity, and reduction of STK38 affects Cdk2-induced centrosome amplification.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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