Thermo Fisher Scientific Omega-hexatoxin-Hv1a Polyclonal Antibody
Arthropod 반응성의 Rabbit Polyclonal Antibody로, Omega-hexatoxin-Hv1a 단백질을 인식합니다. WB 및 ELISA에 사용 가능하며, 고순도 Protein G 정제 제품입니다. 연구용으로만 사용되며, 비진단용입니다.
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- PA5144389
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Applications
Western Blot (WB)
- Tested Dilution: Assay-dependent
ELISA (ELISA)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Arthropod |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Hadronyche versuta Omega-hexatoxin-Hv1a protein (1–37aa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 4 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.03% Proclin 300 |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_3090368 |
Target Information
Reversibly and voltage-independently blocks both mid-low- (M-LVA) and high-voltage-activated (HVA) calcium channels in cockroach DUM neurons (PubMed:17610847).
Is lethal to many insect species but not toxic to mammals (PubMed:9228949, PubMed:16779650).
May target the insect high-voltage-activated calcium channel Dmca1D. Also inhibits acarines calcium channels.
An extremely high toxin concentration partially inhibits Cav1.2/CACNA1C, Cav2.1/CACNA1A, and Cav2.2/CACNA1B calcium channels of rats.
As for omega-AcTx-Hv2a, injection of this toxin into lone star ticks (Amblyomma americanum) causes curling of all eight legs into closed loops.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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