Thermo Fisher Scientific NKCC1 Polyclonal Antibody
Rabbit 유래 다클론성 NKCC1 항체로 인간 시료에 반응하며, IHC(P)에서 7.5–10 µg/mL 농도로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS에 0.1% sodium azide가 포함된 액상 형태. 세포 이온 균형 및 부피 조절 연구에 적합.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 7.5–10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 19 amino acid peptide from N-terminus of human SLC12A2 / NKCC1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.6 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C (short term). For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550484 |
Product Specific Information
Percent identity with other species by BLAST analysis:
- Human, Gorilla (100%)
- Gibbon (89%)
- Monkey, Marmoset, Ferret, Dog, Panda (84%)
Target Information
NKCC1 mediates sodium and chloride transport and reabsorption.
This membrane protein is important in maintaining proper ionic balance and cell volume.
NKCC1 is an electrically silent transporter that mediates sodium and chloride reabsorption and is phosphorylated in response to DNA damage.
Three transcript variants encoding two different isoforms have been identified for NKCC1.
Diseases associated with SLC12A2 include Basosquamous Carcinoma and Metatypical Basal Cell Carcinoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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