Thermo Fisher Scientific TNFAIP8L1 Polyclonal Antibody
TNFAIP8L1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody입니다. 인간 시료에 반응하며 Western blot에 적합합니다. 합성 펩타이드 면역원으로 제작되었고, 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA569889
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 0.2–1.0 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of human TNFAIP8L1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_2688786 |
Product Specific Information
This target displays homology in the following species:
- Cow: 93%
- Dog: 100%
- Horse: 100%
- Human: 100%
- Mouse: 93%
- Rat: 100%
Target Information
Tumor necrosis factor, α-induced protein 8-like 1 (TNFAIP8L1) is a 186 amino acid protein belonging to the TNFα-IP8 family.
Members of this family are induced by nuclear factor-κB (NFκB) and tumor necrosis factor (TNF), with TNF induction dependent on NFκB activation.
TNFAIP8L1 proteins act as negative mediators of apoptosis and may play a role in tumor progression.
They suppress TNF-mediated apoptosis by inhibiting caspase-8 activity, preventing BID cleavage and caspase-3 activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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