Thermo Fisher Scientific Synaptotagmin 10 Polyclonal Antibody
Western blot, IHC, ICC, ELISA 등 다양한 응용에 사용 가능한 다클론 항체. 인간, 마우스, 랫트 반응성. Rabbit IgG 기반으로 Protein A 정제. -20°C 보관, 1 mg/mL 농도. 신경계 IGF1 분비 관련 연구에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:200 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human Synaptotagmin X (amino acids 351–435) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
SYT10 is a Ca²⁺ sensor specifically required for the Ca²⁺-dependent exocytosis of secretory vesicles containing IGF1 in neurons of the olfactory bulb. Exocytosis of IGF1 is essential for sensory perception of smell. SYT10 is not involved in Ca²⁺-dependent synaptic vesicle exocytosis. It functions through Ca²⁺ and phospholipid binding to the C2 domain, where Ca²⁺ induces binding of the C2 domains to phospholipid membranes and assembled SNARE complexes, contributing to exocytosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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