Thermo Fisher Scientific SIN3A Recombinant Rabbit Monoclonal Antibody (8V5B6)
Thermo Fisher의 SIN3A Recombinant Rabbit Monoclonal Antibody (8V5B6)은 Human, Mouse, Rat 시료에서 SIN3A 단백질 검출에 적합합니다. WB, IHC, ICC/IF, ELISA 등 다양한 응용 가능. 고순도 Affinity Chromatography 정제, 안정적인 액상 형태로 제공.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 8V5B6 |
| Immunogen | Synthetic peptide corresponding to amino acids 1174–1273 of human mSin3A (Q96ST3) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.2 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 0.05% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2911923 |
Product Specific Information
- Positive test controls: Mouse testis, Rat testis
- Immunogen sequence:
YKMVYVIKSE DYMYRRTALL RAHQSHERVS KRLHQRFQAW VDKWTKEHVP REMAAETSKW LMGEGLEGLV PCTTTCDTET LHFVSINKYR VKYGTVFKAP
Target Information
Mammalian Sin3 (mSin3) is a 150 kDa protein closely related to the yeast SIN3 repressor protein involved in transcriptional repression of many genes. There are two mammalian isoforms, mSin3A and mSin3B.
Containing four paired amphipathic helix (PAH) domains, mSin3A and mSin3B interact with several transcriptional repressor proteins such as HDAC1, HDAC2, RbAp46, MeCP2, Mad/Max heterodimer, SMRT, and N-CoR.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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