
Thermo Fisher Scientific FCER2 Monoclonal Antibody (OTI6C2), TrueMAB
FCER2 단백질을 인식하는 Mouse IgG2a 단일클론 항체로, Western blot과 IHC(P)에서 검증됨. Human 시료에 반응하며, Affinity chromatography로 정제됨. PBS/BSA/glycerol buffer에 보관되며, -20°C에서 안정적임. 연구용으로 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6C2 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 48–321 of human FCER2 produced in SF9 cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
CD23 is a 45 kDa glycoprotein present on a subpopulation of freshly isolated peripheral blood and tonsil B cells and strongly expressed on EBV-transformed B lymphoblasts. The CD23 molecule is identical to the low-affinity IgE receptor found on B cells. Expression of CD23 has been detected in neoplastic cells from cases of B cell chronic lymphocytic leukemia and some cases of centroblastic/centrocytic lymphoma. Functionally, CD23 is involved in B cell growth and differentiation, and IgE production. CD23 also has a soluble form that acts as a potent mitogenic factor. Diseases associated with CD23 dysfunction include chronic conjunctivitis and chronic lymphocytic leukemia.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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