Thermo Fisher Scientific B7-H6 Polyclonal Antibody
Rabbit polyclonal antibody against human B7-H6 (NCR3LG1). Recognizes transmembrane ligand expressed on tumor cells. Useful for studying NK cell activation and tumor immunology. Supplied as liquid, unconjugated, 0.3 mg/mL concentration.
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Thermo Fisher Scientific B7-H6 Polyclonal Antibody
제품 개요
Rabbit polyclonal antibody recognizing human B7-H6 (NCR3LG1), a transmembrane ligand expressed on tumor cells and involved in NK cell activation.
제품 사양
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human NCR3LG1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2644528 |
Product Specific Information
Immunogen sequence:
TPLNDNVTIF CNIFYSQPLN ITSMGITWFW KSLTFDKEVK VFEFFGDHQE AFRPGAIVSP WRLKSGDASL RLPGIQLEEA GEYRCEVVVT PLKAQGTVQL EVVASPASRL LLDQVGMKEN EDKYMCESSG FY
Highest antigen sequence identity to the following orthologs:
- Mouse: 27%
- Rat: 28%
Target Information
B7-H6 (NCR3LG1) is a transmembrane endogenous ligand expressed on tumor cell surfaces. It binds to NKp30 present on NK cells, leading to NK cell activation and target cell cytolysis.
B7-H6 is not constitutively expressed on normal tissue, though expression under certain conditions is under investigation.
Detected on circulating pro-inflammatory CD14(+)CD16(+) monocytes in some patients with sepsis.
주의사항
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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