
Thermo Fisher Scientific Human NIK Synthetic Peptide
인간 NIK 단백질의 카복시 말단 17개 아미노산 서열을 포함한 합성 펩타이드로, PA5-19871 항체의 블로킹 펩타이드로 사용 가능. NF-κB 신호 전달 연구에 활용되며, 고순도 액상 형태로 제공. 연구용으로만 사용.
- 카탈로그번호
- PEP0007
- 판매단위
- pk
카탈로그
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 17 amino acids near the carboxy terminus of human NIK.
PEP-0007 can be used as a blocking peptide with polyclonal antibody PA5-19871.
Target Information
MAP3K14 (NIK) is structurally related to MAP3Ks. MAP3K14 phosphorylates and activates CHUK (IKKalpha) and IKBKB (IKK beta), which in turn phosphorylate IkB-alpha, releasing NF-KappaB leading to up-regulation of inflammatory response genes. This kinase binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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