Thermo Fisher Scientific IL4R Polyclonal Antibody
IL4R 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, Western blot, IHC, ICC, Flow cytometry, ELISA 등 다양한 응용에 적합. Human과 Mouse 반응성, Protein A 정제, 고농도(1 mg/mL) 액상 형태로 안정적 보관 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human IL4R, amino acids 201–300 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
IL4 Receptor alpha (IL4RA) is the alpha chain of the interleukin 4 receptor, which binds to both interleukin 4 and interleukin 13 to regulate IgE production, chemokine and mucus production at sites of allergic inflammation. The IL4 response promotes Th2 differentiation. The secreted extracellular domain of IL4R alpha (sIL4R alpha) can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells but has no signaling abilities. Allelic variations in the IL4RA gene have been associated with atopy, which can manifest as allergic rhinitis, sinusitis, asthma, or eczema.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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