Thermo Fisher Scientific PDE2A Monoclonal Antibody (OTI4D10), TrueMAB
PDE2A 단백질을 인식하는 마우스 모노클로날 항체로, Western blot, ICC/IF, Flow Cytometry에 사용 가능. 인간 PDE2A에 반응하며, 무보존제 Lyophilized 형태로 제공. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4D10 |
| Immunogen | Full length human recombinant protein of human PDE2A produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of about 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
PDE2A (phosphodiesterase 2A) is a 100 kD cyclic nucleotide phosphodiesterase with three isoforms (PDE2A1, PDE2A2, PDE2A3) generated by alternative splicing.
It degrades both cAMP and cGMP, more efficiently degrading cGMP. PDE2A is highly expressed in the brain, particularly in the cerebellum and neocortex.
It is implicated in erectile dysfunction and regulation of endothelial cell barrier function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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