Thermo Fisher Scientific GPN1 Polyclonal Antibody
Human GPN1 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western blot, IHC, ICC/IF에 적합. 항원 친화 크로마토그래피로 정제되었으며 PBS/glycerol buffer에 보관. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | - |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human GPN1. Recombinant protein control fragment (Product #RP-102748). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2642149 |
Product Specific Information
Immunogen sequence:
ALDAGTAKDS LSPVLHPSDL ILTRGTLDEE DEEADSDTDD IDHRVTEESH EEPAFQNFMQ ESMAQYWKRN NK
Highest antigen sequence identity to orthologs:
- Mouse: 81%
- Rat: 83%
Target Information
Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII) (PubMed:20855544, PubMed:21768307).
May act at an RNAP assembly step prior to nuclear import (PubMed:21768307).
Forms an interface between the RNA polymerase II enzyme and chaperone/scaffolding proteins, suggesting that it is required to connect RNA polymerase II to regulators of protein complex formation (PubMed:17643375).
May be involved in nuclear localization of XPA (PubMed:11058119).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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